And pineapple sounds a good idea too! Then starting in June 2014, I had 15 doses of Radiotherapy. My experience was that how I felt after my following treatments was similar to my reaction after the first treatment. Taxotere is part of a family of drugs known as taxanes that work by preventing cell growth. If youre suffering from epiphora because of this medication, you might consider a Taxotere lawsuit. July 16, 2018. Many people lose alltheir body hair, including their eyebrows and eyelashes. Patients on the TAXOTERE arm received TAXOTERE (T) 75 mg/m 2 by intravenous infusion on day 1 followed by cisplatin (P) 100 mg/m 2 administered as a 30-minute to three-hour intravenous infusion, followed by the continuous intravenous infusion of fluorouracil (F) 1000 mg/m 2 /day from day 1 to day 4. Any suggestions for the pain? Got better on Day 6 and got better on Day 7. It is so much easier than the taxotere, virtually no side effects at all. My husband has booked a cottage break in July to hopefully celebrate the end of chemo before my surgery. There are a number of things you can do to manage the side effects of docetaxel. Gone too far now to stop just need to finish the course. I ended up in hospital 4 days after treatment.. I have a good support system at home who do just about everything as I have been bed or sofa bound for the last 10 days with just small walks around the house to keep the circulation going. Signs of a reaction can include: shortness of breath or difficulty breathing, swelling of the face, lips, tongue or throat, trouble swallowing, chest pain, rash, flushing, hives or itching or a decrease in blood pressure. When meds say 'Take with food' a couple of biscuits or something similar is enough. I am sorry to read that the chemo is hitting you so hard.If there is a magic answer i never found it but the things that were usefull to me were -dont eat befor chemo and walk afterwards.If you can get your body going-even if it is to the end of the road and back and you feel like **** I found it seemed to get your system going at least a bit. Your hair may become thin, brittle, or may fall out. In its mechanism of action, Taxotere prevents the inner structures of cancer cells from building, which stops cell division and eventually leads to cancer cell death. All content 2023 Trustees of the University of Pennsylvania. I took Oestrogen suppressing tablets over July and August and restarted chem beginning of September with the FEC. Docetaxel can pass into body fluids (urine, feces, vomit). I was diagnosed in Feb 2013 and had a rt mastectomy op in March. It was neoadjuvant chemotherapy, including Taxanes (Taxotere), Carboplatin, and Trastuzumab (Herceptin). *Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). Humor can also lessen anxiety and discomfort, allowing cancer patients to talk more openly about their concerns and fears. You may have some of the above symptoms or you may not. It was tough going, but I got there. Ranking the Cowboys backup QB options from worst to best. Grapefruit can change how your body absorbs this medication. I only have one more left now as it was my 5th cycle of chemo regimen FEC x 3 then Docetaxel x 3 . I am just hoping they settle quicker than before as I am more prepared with medications from knowing what happened last time. Last injection today. Have had one cycle of that and have the second next week. This may vary depending on whether the number of blood cells has returned to normal between each cycle. Operation will be 4 weeks after my last dose. I am still needing sofa days, but hoping to get out soon for a much needed change of scenery and breath of fresh air. It causes numbness or a tingling feeling in the hands and/or feet, often in the pattern of a stocking or glove. The care I have had from diagnosis to today has been quick, I begin Radiotherapy begining of March. This combination of meds had the remarkable result of shrinking my very large tumor by a full 50 percent! Taxotere is a chemotherapy drug that is used to treat various cancers such as breast cancer, non-small cell lung cancer, prostate cancer, gastroesophageal cancers, and head and neck cancers. I never threw up really, but I had underlying nausea all the time. Chemotherapy drugs can deplete your supply of red blood cells, the cells that carry oxygen throughout your body. At that time, TAXOTERE was typically used for advanced prostate cancer, after all other treatments had failed. Then yesterday; she was miserable all day; felt weak; and couldn't really describe the bad feeling in her body. Exposure of an unborn child to this medication could cause birth defects, so you should not become pregnant or father a child while on this medication. In 2022 . Thank you, i hope your recovery continues to bring good news and health. It has now been almost exactly 4 days (96 hours) since. I feel more at ease in this second week of treatment and hope to have recovered enough to have my next cycle. 01-06-2015 02:21. I was better prepared for the following two though. Fellow sufferers, keep your hopes up. Get the B**tard out for good! Remember, not all advice works for everyone. Hi, Week Three was Im actually feeling pretty good and then you go right back to Week One. It's an option that, over the last twenty years, medical teams and patients believed was the best course of action. Cyclophosphamide is a type of chemotherapy medicine . OR. ), and have smoked and used alcohol for most of my life. What Is the Taxotere Mechanism of Action? Itis designed to target malignant cancer cells in your body. In some ways was easier, in others was more taxing (pun intended)! Avoid things that may worsen the symptoms, such as heavy or greasy/fatty, spicy or acidic foods (lemons, tomatoes, oranges). Hopefully this will work out and spare me the ordeal of last time. TC ( Taxotere and cyclophosphamide) is a common chemotherapy regimen given for localized breast cancers that require chemotherapy. Pineapple is good for helping the nasty taste and I know someone who sucked frozen pineapple cubes and this helped her a lot. This chemo certainly throws everything at us to endure. Try saltines, or ginger ale to lessen symptoms. I found it helped a great deal so I do hope you get to enjoy yours. Your fingernails/toenails may become dark, brittle or fall off. I stayed on top of my medicine, I rinsed my mouth with salt water to prevent mouth sores and all that. You may also need to take your temperature at home during your treatment to stay on top of fevers. Your oncology care team can recommend medications to relieve diarrhea. I lost my hair and everything, but the chemo itself was not that bad. starting at end of cisplatin infusion (2.4)See full prescr ibing information for TAXOTERE. xx, I too had terrible 1st cycle and likewise was admitted due to high temp feel better now but due next cycle on we'd feeling scared I have 3 very young children am incurable breast cancer not sure can cope am now on injection to keep blood count up, Sorry to hear of your experience Jazzy, I know it's not pleasant. Platelets help your blood clot, so when the count is low you are at a higher risk of bleeding. I have weaned myself off the Co-Codamol as I don't want to rely on it and the bone aches have reduced considerably now. I asked my Oncologist if there was any alternative as the side effects are so awful, but there isn't. The end is now in sight and just keep thinking what a good job the chemo is doing getting rid of this nasty disease. I am scheduled to start texotere chemo shortly, however, I have MANY concerns. My wonderful wife took me away between chemo and Rads, it was a truly enjoyable break, 5 days in a cabin in the woods (provided free by The Willow Foundation). Thanks for being such a grand support for her. The most common chemotherapy drug for prostate cancer is docetaxel (Taxotere), which is usually given with prednisone, a steroid medicine. I had constipation, diarrhea so bizarrely both, and then the nausea. Please. In some cases, you might feel extra hungry or gain weight. It, like other chemotherapy medications, can have severe side effects. My concern is that with my weight, history of smoking and alcohol my body will not tolerate all of this. Genoa M. (Breast Cancer, Invasive Ductal Carcinoma [IDC], Stage 3, HER2+). Use seasonings like basil, oregano, or rosemary to add flavor. fatigue. Found the freeze gell hit the joint areas better and gave relief. Was 48mu for EC but took 7Tax was 30mu. We needed to make a spread sheet of what pills to take and when. Progression-free survival was 2-3 months for both groups. No wonder you were dreading it. It doesnt have to be anything big. I need to eat better to keep up my energy which is at an all time low. You don't sound negative, you just sound disheartened that after following all advice you are still suffering and also that you are finding treatment difficult. I can't say I am looking forward to next cycle but just want it over. Your healthcare provider can recommend medications and other strategies to help relieve pain. I've just had my first Docetaxel 5 days ago and boy am I sufferingshooting painsin lower back, kidney area,legs andshoulders for two days now. I spent a week in hospital after the 3rd Taxotere + radiotherapy. * To protect your identity do not use your full name. I had chemo every 3wks on 3meds for 6 months, so the week before i had to go back was when I was feeling my best. Add extra flavor to meat or fish by marinating it in sweet juices, sweet and sour sauce, or dressings. That seems to help me. Edema happens when fluid collects under your skin and within the tissues outside your circulatory system. Like many have stated, I was OK for the two days following and then felt like sh*t for two or three days and then was on the mend and better until the next treatment. Nutrition is an important part of your care. It takes the edge off the pain which means taking paracetamol with it actually works. I would go to work when I was able to and just did what I could. Pain starts on day 3 and lasts 6 days. So would recommend this. I have at times reached my lowest and questioned if I can continue to put my body through this poison. I have finished 4 cycles so far with 4 more to go. Actually, I had a really nice time as it was. After starting docetaxel, many men experience the improvements in disease-related symptoms, including pain, fatigue and loss of energy. Even if your menstrual cycle stops or you believe you are not producing sperm, you could still be fertile and conceive. I'll be starting this Thursday and have 10 steroids to take Wednesday night and then whatever they give me as pre-meds. Its often very difficult to treat edema caused by cancer and chemotherapy. The U.S. Food and Drug Administration originally approved the drug in 1996. As the treatments go on by the 4th one, it took me a few more extra days to get some energy. Your nurse will check you for signs of a reaction during your treatment. It's important to take things day by day. It took a few months for my taste to come back. You may notice chills, a sore throat, achiness, and swollen glands and lymph nodes. TAXOTERE (docetaxel) injection, for intravenous use . I would have Gemcitabine on week one. neuropathy, or pain caused by nerve damage. Alternative therapies can help for relaxation althrough at th emoment i go for the glass of wine cure. I wish you the best with these meds. Treatment . Other effects for me are tingling in feet, skin peeling off, mostly in feet, toe nails highly sensitive. I wish I rang sooner. Doctors may lower the dose or prescribe drugs that reduce the risk of allergic reactions to deal with these types of side effects. worst daysfor me it was the week after the infusion..I just fall apart.tired, ache, intestinal issuesetc. I am trying to keep focused and positive to get through this. In fact, Taxol is the top-selling cancer drug worldwide. Best of luck to you all xxx, I would be happy to receive news and updates from Cancer Chat, NICE suspected cancer referral guidelines, Cancer Research UK for Children & Young People. Need to get myself prepared for the next one. A post shared by Soulcake (@soulcake) on Jul 18, 2017 at 9:40pm PDT. Taxol once every 3 weeks: 86.5% Taxotere once every 3 weeks: 87.3% Taxotere once a week: 86.2% Some doctors have wondered whether a taxane has benefits for women diagnosed with hormone-receptor-positive breast cancer. For now, just concentrate on YOU! So far I have been ok on the 2nd cycle just starting to feel the side effects kicking in this evening . Can eat, not been sick, not taken antisickness meds, but nausia with ukky taste but poor sleep got worse. Really, you already have otherwise you wouldn't be 4 sessions down with only 2 more to go. Fluid build-up can cause heart failure and poor blood circulation. Its just moving because I felt it moved the chemo through my body faster. pathology report has our Onc ordering additional scans. I am hopeful that the next two cycles will be less of a shock to the system. Protein helped and exercise helped me. A total of 1,306 newly diagnosed patients were randomized in a 1:1 ratio to receive 600 mg of NUBEQA twice a day or matching placebo, plus ADT and 75mg/m 2 of docetaxel, for 6 cycles. I had the sore mouth too but I must have been one if the lucky ones as I do not remember too many other side effects - it was 7 years ago. My kids are 10 and 5. I got off lightly on the 4 AC, only had a couple of very bad days each cycle. I followed all the advice and recommendations given by the medical team and tried to be positive about the treatment working to fight the cancer but it has been hard. Your labs will be closely monitored prior to each dose of docetaxel and the dose may be decreased or held if your liver function is not normal. They can help you decide what will work best for you. My own experience to date As of day 8 after my first Tax blast, I currently hate Tax and FEC in equal measure. Men who are treated with this medication should use effective birth control during and for 4 months after the last dose. Search deep within yourself, you will find the strength. Did they check your bloods in A&E?? The content on this site is for informational purposes only. I don't think you have "gone wrong" anywhere, more that T has hit you hard and you would like to be in a better place for the next 2. Shari S. (Breast Cancer, Invasive Ductal Carcinoma (IDC),Triple Positive, Stage 4). Carry on being her strength and pass on my love to her xx. The median overall survival (OS) was 81 months . Best wishes Jules xxx. I was severely feverish, my whole body ached to the point that I felt like I was in a can crushing machine, I felt sick and my mouth was worse than ever (it had been bad all the way through). 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